Showing posts with label fatty acids. Show all posts
Showing posts with label fatty acids. Show all posts

Monday, April 4, 2011

Lies, and the Vegans that tell them

I've been busy the last few days and haven't had a chance to write anything. While going through my email tonight, I have yet more spam from the Eat Right America morons. Tonight's theme was too much not to write about. It basically said I should eat less meat but they weren't trying to promote veganism. Yeah and I'm the Pope. {/snark}

The thing though that prompted me to write though is this, they lie. Liars, liars, pants on fire. (Should I be surprised? Probably not, most people propagating the vegan diet have to lie because if they told the truth, few would be vegan.) So what reason do they give for eating less meat?
"In fact, [animal products] are rich in substances that scientific studies have shown to be associated with incidence of cancer and heart disease: saturated fat, cholesterol and arachidonic acid, an inflammatory acid found only in animal products." [emphasis mine]

Ah yes, the big old boogie men of saturated fat and cholesterol. We already know that's BS, but what is this arachidonic acid? Only an essential fatty acid, vital for visual and cognitive development of infants and found in breast milk. In fact, if the mother is deficient they need supplementation. Arachidonic acid is vital for neural function. And these asshats are basically saying you don't need it.

See this kind of crap makes me madder than hell. Why, do you ask? Because these idiots have an air of authority, and many people who read this crap will take them at their word without looking into what the thing actually does.

They go onto say that meat causes osteoporosis. Yes, you read that correctly, I'm not making this up.
"In addition, animal products are very acidic for the body and cause calcium to be released from the bones to help neutralize the acid in the blood. This in turn leads to calcium loss and weak, brittle bones."
That's gotta be the biggest load of BS that I've read. And do they quote a source, a study? Hell no, of course they don't. If it were true, that eating animal products made your bones brittle, then body builders would be breaking bones all the damned time because most of the ones that I've read on the internet are eating paleo. These idiots just keep piling it on. Forget the shovel, someone get them a backhoe so they can dig their lying asses deeper faster. Maybe the pit they're digging will cave in and bury them. But remember, they're not advocating a vegan diet by any means. *rolls eyes*

Monday, March 14, 2011

When you're metabolically screwed up, the study of "normal" people tells you nothing

Is it possible that sugar is the culprit behind metabolic syndrome? It seems that glucose and fructose together are bad news. I found an article to read last night, and saved it because it was late at the time. I've spent the last couple of hours reading it (and looking up biochemistry terms LOL).

The following are pieces of the article that I found the most interesting. Remember, if you don't have access to scholarly databases and want to read the article, you should be able to get a log-in for your local public library's proxy and then be able to look up journal articles.


1.) Low glycogen promotes insulin action, whereas high glycogen promotes insulin resistance. Glycogen is primarily elevated by eating carbohydrates.
"Prevention of glycogen synthesis, by fasting or feeding a low-carbohydrate/high-fat diet, results in a persistence of contraction and insulin-mediated glucose transport that lasts as long as carbohydrates are not consumed. This line of work shows that low glycogen promotes increased insulin action, whereas high glycogen promotes insulin resistance."


2.) People who are metabolically damaged respond more positively to restricting carbohydrate intake than people who are not metabolically damaged.
"That patients with MetS [metabolic syndrome] might be particularly sensitive to carbohydrate restriction was suggested by Cornier et al. [28] who compared the response of obese insulin-sensitive and obese insulin-resistant subjects randomized to either a high-carbohydrate (60%) or lower carbohydrate (40%) diet. Weight loss was similar for the insulin-sensitive group irrespective of carbohydrate level. The most striking result was that only the insulin-resistant group showed a major change in any lipid parameter with a 42% average decrease in TG on lower carbohydrate, and a 27% increase on higher carbohydrate. That individuals with MetS or insulin resistance syndrome respond better to restricting carbohydrates than fat is consistent with intolerance to carbohydrate as the fundamental metabolic problem."


3.) The saturated fat levels in your blood are higher when eating carbohydrates. Go figure.
"If carbohydrate intake were low enough to decrease levels of glucose and insulin, however, a high SFA intake would be processed very differently. We recently showed, for example, a disconnect between dietary SFA and plasma levels of SFA apparently due to the regulatory role of dietary carbohydrate in controlling de novo lipogenesis (DNL)...

A notable result was that, despite a 3-fold higher intake of dietary saturated fat during the VLCKD [very low carb], saturated fatty acids in TG [triglyceride] and cholesteryl ester were significantly decreased compared to subjects consuming the LFD [low fat diet]. That this was due to a decrease in DNL [de novo lipogenesis] was shown by a corresponding reduction in palmitoleic acid (16:1n-7), an endogenous indicator of this process."

4.) Glucose, independent of insulin, also has an effect on fat storage.
"Expression of the lipogenic genes occurs without any apparent effect of insulin indicating one way in which glucose directly regulates nutrient partitioning."

5.) It's not about calories per se.
"It is worth noting that many changes in lipid metabolism during fasting are due to the specific removal of carbohydrate as opposed to a general elimination of calories."

6.) This was the most interesting one. Insulin resistance occurs in the muscles and liver first, and when this happens, your body has no choice but to convert the glucose in your blood stream into fat (either de novo lipogenesis or manufacture of triglycerides). This is an interesting concept on a few levels. One thing is, any studies done on people who are NOT insulin resistant could be IRRELEVANT for those who are.


("There are truths which are not for all men, nor for all times."--Voltaire)
"The fate of a dietary carbohydrate load in lean insulin-resistant and insulin-sensitive men was determined using a combination of 1H and 13C NMR spectroscopy to assess liver and muscle triglyceride and glycogen synthesis, respectively, and deuterium enrichment to assess de novo lipogenesis. The insulin-resistant men showed impaired skeletal muscle and hepatic glycogen formation following intake of dietary carbohydrate. Consistent with the paradigm presented in Fig. 1, dietary carbohydrate in the insulin-resistant group was instead diverted toward hepatic DNL [de novo lipogenesis] and TG [triglyceride] synthesis that contributed to a significant increase (60%) in plasma TG levels."

7.) A short study probably shows jack when it comes to metabolism.
"The time course of metabolic adaptations is also variable; some lipolytic adaptations occur within a week (e.g., gene expression of FAT/CD36 and b HAD) while others take longer (e.g., FABP and CPT I). Several weeks may be necessary for complete switch to optimal fat utilization."

8.) Fatty acid oxidation is increased with carbohydrate restriction. According to Lippincott's Illustrated biochemistry text, fatty acid oxidation is the primary source of fuel when starving. We know that decreased carbohydrate intake is similar to starving when it comes to how your body mobilizes fat stores.
"The hormonal changes that accompany carbohydrate restriction, fasting or continued physical activity lead to inhibition of glycogen synthesis and inactivation of acetyl-CoA carboxylase and a fall in malonyl-CoA levels which, in turn, relieves inhibition of carnitine transport and thereby stimulates fatty acid oxidation."

All very interesting stuff.

Thursday, February 24, 2011

Biochemistry for Artists?

We decided to order a biochemistry text book to read. I know, most people don't read biochemistry text books for fun, but then, we're not really like other people. I read the first chapter last night on amino acids, and was wishing that I remembered more of the one chemistry class that I had years ago, and that I had taken more of them. Luckily mum-in-law has a master's degree in Mycology... I'm relying on her to explain some of what I read LOL

I realized reading it, that most "professionals" that are telling you what to eat, don't know anything about biochemistry. And the prime example, is registered dietitians. I always thought that most people who became registered dietitians did so because they couldn't hack it in a real college. I figured most of them were beauty school dropouts. I suppose it just seems that way. They do have to have a four year degree and pass an exam, but there doesn't seem to be any standards about how many science classes they take, or if they even have to have an understanding of biochemistry. It seems they can have a four year degree in food service management with just the minimal science classes required to graduate with a bachelor's degree, and become one. I'm sorry, but there's something wrong with that.

Registered dietitians used to have the job of taking the orders of patients in hospitals for what they wanted to eat for their meals. Now, registered dietitians tell you what you should eat, with little or no understanding of biochemistry or the roles of fats and cholesterol in the VITAL FUNCTIONING OF CELLS. When you listen to dietitians, you're letting someone with an inadequate education and understanding of human biological processes tell you what to eat. You don't let your hairdresser perform brain surgery on you. Listening to a registered dietitian about what you should eat, is for lack of a better word, stupid.

It ought to be that anyone who wants to dispense dietary advice as a "professional" have a degree in biochemistry. Otherwise, they don't understand what they're advocating. If registered dietitians had biochemistry degrees, they wouldn't tell you that fat is bad for you.